"Once the school had been opened, the King said that the Ashanti Confederacy wanted the school to be a part of it, would I mind? I was absolutely delighted and the Asantehene undertook to provide the stool which would symbolise the school’s membership of that august body."

- Rev. Sidney N. Pearson, (1916-2003)

Prempeh College, the Asante Royal Boarding School for Boys is the Kings College of Ghana. Founded in 1949 and incorporated into the Asante Confederacy by Asantehene Sir Osei Agyemang Prempeh II, it has produced most of the men who compose the mass of our Chieftancy institution - from Kumawuhene, Essumajahene, Akyerensuahene, Akyempemhene of Asante, Akyempemhene of Akyem, the late Okyehene, Asuonwunhene, New Dwabenhene, Adansihene, to Mamponghene, and many more. Even the current Asantehene, King Osei Tutu II, enrolled at Prempeh before transferring to another school.

National records has also shown that Prempeh College has produced more doctors in Ghana than any other school. According to Registrar of the University of Ghana, by 1974 Prempeh College had sent more students to medical school in Ghana than any other school. In one year, 1967/68 nearly all our A-Level Science students went to Medicine. In 1967 June A-Levels, all 25 candidates presented for the A-Levels in Science qualified for admission to the University of Ghana. All the 100% candidates recieved 2 or more passes which qualified them for the University entry. 10 obtained 4 principal passes, 10 three passes and 5 two passes. There were in all 10 distinctions in a total of 10 distinctions on both Science and Arts. Nearly all of them went to Medical School. It was so unheard of to find so many students from one school make it there. The result is that a laarge majority of Ghana's doctors are Prempeh College Alumni.

Among these are Dr. Akosah, the Immediate-Past President of Ghana Medical Association and Director-General of the Ghana Health Service; Dr. Asamoa-Baah, W.H.O. Assistant Director General in charge of Communicable Diseases who has global responsibilities in the health delivery system throughout the world; Dr. Asafo-Adjei, former CEO of Komfo Anokye Teaching Hospital; Dr. K.O. Adade, Chief Medical Officer of Greater Accra; Dr. Emmanuel Tuffuor, President of GhanaCare who was recently featured in the New York Times and whose work has been endorsed and cited by the World Bank/IMF as "one of the greatest contributions of the advancement of health in the developing word;" Dr. Joseph William deGraft Johnson Riverson, Executive Director of Donor Relations & Coordinator of Trachoma Program, World Vision U.S., who has lived a life of exemplary devotion to humanitarian causes; Prof. E. Tsiri Agbenyega, Dean of the School of Medical Sciences of The Kwame Nkrumah University of Science & Technology; Dr. Jacob Jordan Lamptey, that renowned psychiatrist who operates The Valley View Clinic (est. 1987) - the only general practice in Ghana with special interest in psychiatry and related problems in a country where psychiatry practice and psychiatrists are rare; and Dr. Kweku Ghartey, an internationally renowned retinal surgeon at the Massachusetts General Hospital, who was ranked one of "America's 100 Best Doctors" by US News & World Report Magazine.

Other Prempeh luminaries include Dr. Kwabena Dufuor, former Governor of Bank of Ghana; His Excellency Mr. JA Kufuor, President of Ghana; Mr. Yeboah-Amoah, CEO of The Ghana Stock Exchange; Prof. S.K. Adjepong, immediate-past Vice Chancellor of The University of Cape Coast and current Prrincipal of the Methodist University College; Martin Sannah Kwakwa the renowned journalist who is The Editor of the Australian Associated Press; Jim Kusi, the famous engineer who re-constructed the New York City subway system - the world's biggest and most complex subway system; Mr. Kofi Bonner, Vice President and Chief Administrative Officer of the Cleveland Browns Football Franchise; Derek Appiah, British Telecom Project Manager who was responsible for launching the BT broadband in the whole of mainland UK; Dr. Richard Amoako Baah, Novelist and inventor of the Fuel Filter-Dryer, for which he holds a United States Patent; Rev. Dr. Setri Nyomi, first non-European General Secretary of the World Alliance of Reformed Churches (WARC) - the umbrella body which unites over 77 million Presbyterians, Reformed, Congregational and Waldensian churches all over the world; Dr. Francis Achampong, lawyer and author of a seminal textbook on workplace sexual harassment law, whose book is the only work that devotes several chapters to landmark developments such as third-party and same-sex sexual harassment and the only one that goes beyond merely discussing workplace harassment prevention to discussing risk management of liability for sexual harassment; Professor Kwadwo Asenso-Okyere, Vice-Chancellor, University of Ghana; John Sarpong, Chairman and CEO of Africast Global Media; The Very Rev. Dr. Aboagye-Mensah, Presiding Bishop of the Methodist Church, Ghana; Nana Susubiribi Krobea Asante, President of the Ghana Academy of Arts & Sciences; Prof. Stephen Adei, President of the Chartered Institute of Marketing, Ghana (CIMG) and Director-General of GIMPA (Ghana Institute of Management & Professional Association); Kwaku Sintim-Misa: the great stage dramatist and Mr. Edward Boateng, CNN/Turner International's Regional Director for Europe, a man who has been the driving force behind CNN's penetration in Africa and was awarded a special citation by Turner himself (in 1997) for the job he has done.

[See Selected Amanfoo of Note]

Prempeh is the only College in Ghana to have two of her alumni in one Presidential elections: JA Kufuor of the Class of 58 faced JA Koduah of the Class of 62 in NPP Presidential Primaries. If Felix Amoah of the CP decides to run on the party's ticket, it will be three in all.

The mission of Prempeh College is to serve the community, the nation, and the world by discovering, communicating, and preserving knowledge and understanding in a spirit of free inquiry, and by educating and preparing students to discharge the offices of life with usefulness and reputation. We do this through a partnership of students and teachers in a unified community known as a college.